Search results for "Guest molecules"

showing 5 items of 5 documents

Dimeric resorcinarene salt capsules with very tight encapsulation of anions and guest molecules

2015

Crystallization of N-cyclohexyl ammonium resorcinarene triflate from methanol results in a dimeric capsule capable of trapping two triflate anions and two methanol molecules within a 341 A3 cavity while with 1,4-dioxane as a guest it forms a new larger dimeric capsule with volume of 679 A3 encapsulating four 1,4-dioxane and four water molecules, resulting in packing coefficients of 0.75 and 0.67, respectively.

ChemistryGeneral Chemical EngineeringInorganic chemistrydimeric capsulesGeneral ChemistryResorcinarenelaw.inventionguest moleculeschemistry.chemical_compoundlawPolymer chemistryMoleculeMethanolCrystallizationta116anionsTrifluoromethanesulfonateRSC Advances
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Gated mesoporous silica nanoparticles for the controlled delivery of drugs in cancer cells

2015

In recent years, mesoporous silica nanoparticles (MSNs) have been used as effective supports for the development of controlled-release nanodevices that are able to act as multifunctional delivery platforms for the encapsulation of therapeutic agents, enhancing their bioavailability and overcoming common issues such as poor water solubility and poor stability of some drugs. In particular, redox-responsive delivery systems have attracted the attention of scientists because of the intracellular reductive environment related to a high concentration of glutathione (GSH). In this context, we describe herein the development of a GSH-responsive delivery system based on poly(ethylene glycol)- (PEG-)…

INGENIERIA DE LA CONSTRUCCIONCell SurvivalIntracellular SpaceNanoparticleNanotechnologyAntineoplastic AgentsCONTROLLED-RELEASETRIGGERED RELEASEPolyethylene Glycolschemistry.chemical_compoundINORGANIC NANOPARTICLESQUIMICA ORGANICASYSTEMSPEG ratioQUIMICA ANALITICAElectrochemistrymedicinePOLYMER HYBRID NANOPARTICLESGLUTATHIONEBIOQUIMICA Y BIOLOGIA MOLECULARHumansGeneral Materials ScienceDoxorubicinSpectroscopyDrug CarriersENHANCED PERMEABILITYQUIMICA INORGANICASurfaces and InterfacesGlutathioneIN-VITROMesoporous silicaCondensed Matter PhysicsSilicon DioxideControlled releaseGUEST MOLECULESBioavailabilityDrug LiberationchemistryDoxorubicinDelayed-Action PreparationsDrug DesignNanoparticlesPhenazinesSUPPORTSEthylene glycolOxidation-ReductionPorositymedicine.drugHeLa Cells
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Glucose-triggered release using enzyme-gated mesoporous silica nanoparticles.

2013

[EN] A new gated nanodevice design able to control cargo delivery using glucose as a trigger and cyclodextrin-modified glucose oxidase as a capping agent is reported.

INGENIERIA DE LA CONSTRUCCIONDelivery SystemGuest moleculesSupportsSilicon dioxideCarbon nanotubesResponsive controlled releaseNanoparticleNanotechnologyCatalysischemistry.chemical_compoundGlucose OxidaseQUIMICA ORGANICAQUIMICA ANALITICAMaterials ChemistryOrganometallic CompoundsTriggered releaseGlucose oxidaseHydrogen peroxideColoring AgentsNanodevicechemistry.chemical_classificationbiologyQUIMICA INORGANICAMetals and AlloysGeneral ChemistryMesoporous silicaHydrogen peroxideSilicon DioxideSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsEnzymeGlucosechemistryCeramics and Compositesbiology.proteinBiophysicsNanoparticlesPorosityChemical communications (Cambridge, England)
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Finely Tuned Temperature-Controlled Cargo Release Using Paraffin-Capped Mesoporous Silica Nanoparticles

2011

[EN] Trapped: Mesoporous silica nanoparticles were loaded with a fluorescent guest and functionalized with octadecyltrimethoxysilane. The alkyl chains interact with paraffins, which build a hydrophobic layer around the particle (see picture). Upon melting of the paraffin, the guest molecule is released, as demonstrated in cells for the guest doxorubicin. The release temperature can be tuned by choosing an appropriate paraffin. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Models MolecularINGENIERIA DE LA CONSTRUCCIONGuest moleculesParaffinsParaffin waxesNanoparticlemesoporous materialsMCM-41Phenazine derivativeFunctionalizedCell survivalNanoparticleQUIMICA ORGANICAChemical structureX-Ray DiffractionSafranin tSilicon dioxideControlled releaseAlkyl chainDrug CarriersMicroscopy ConfocalMolecular StructureOctadecyltrimethoxysilaneSurface propertyTemperatureSilicaGeneral MedicineChemistryAntineoplastic agentParaffinHeLa cellPorosityHumanMaterials scienceDrug carrierX ray diffractionSurface PropertiesMesoporous silica nanoparticlesNanotechnologyAntineoplastic AgentsMesoporousCatalysisDrug interactionsArticleMicroscopy Electron TransmissionHumansCell survivalDrug effectDelayed release formulationHydrophobic layersQUIMICA INORGANICAGeneral ChemistryMesoporous silicaMolecular gatesMesoporous materialsMcm 41Confocal microscopyDrug effectSolubilityDoxorubicinDelayed-Action Preparationsdrug deliveryDrug deliveryNanoparticlesPhenazinesnanoparticlesMesoporous materialcontrolled releasemolecular gatesTransmission electron microscopyHeLa CellsAngewandte Chemie
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Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant)

2016

Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP).

NANOCAPSULESRESPONSIVE CONTROLLED-RELEASESarinGATED MATERIALSNanoparticle02 engineering and technologyCHEMICAL WARFARE AGENTS010402 general chemistry01 natural sciencesBiochemistryNanocapsuleschemistry.chemical_compoundQUIMICA ORGANICADESIGNSomanmedicineRhodamine BOrganic chemistryDRUG-DELIVERYPhysical and Theoretical ChemistryNerve agentNANOCONTAINERSChemistryQUIMICA INORGANICAOrganic ChemistryDNAMesoporous silica021001 nanoscience & nanotechnologyGUEST MOLECULES0104 chemical sciencesDiisopropyl fluorophosphateDCNP0210 nano-technologymedicine.drugNuclear chemistryOrganic Letters
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